BackgroundAn increasing number of studies utilize intracranial electrophysiology in human subjects to advance basic neuroscience knowledge. However, the use of neurosurgical patients as human research subjects raises important ethical considerations, particularly regarding informed consent and undue influence, as well as subjects’ motivations for participation. Yet a thorough empirical examination of these issues in a participant population has been lacking. The present study therefore aimed to empirically investigate ethical concerns regarding informed consent and voluntariness in Parkinson’s disease patients undergoing deep brain (...) stimulator (DBS) placement who participated in an intraoperative neuroscience study.MethodsTwo semi-structured 30-minute interviews were conducted preoperatively and postoperatively via telephone. Interviews assessed participants’ motivations for participation in the parent intraoperative study, recall of information presented during the informed consent process, and participants’ postoperative reflections on the research study.ResultsTwenty-two participants (mean age = 60.9) completed preoperative interviews at a mean of 7.8 days following informed consent and a mean of 5.2 days prior to DBS surgery. Twenty participants completed postoperative interviews at a mean of 5 weeks following surgery. All participants cited altruism or advancing medical science as “very important” or “important” in their decision to participate in the study. Only 22.7% (n = 5) correctly recalled one of the two risks of the study. Correct recall of other aspects of the informed consent was poor (36.4% for study purpose; 50.0% for study protocol; 36.4% for study benefits). All correctly understood that the study would not confer a direct therapeutic benefit to them.ConclusionEven though research coordinators were properly trained and the informed consent was administered according to protocol, participants demonstrated poor retention of study information. While intraoperative studies that aim to advance neuroscience knowledge represent a unique opportunity to gain fundamental scientific knowledge, improved standards for the informed consent process can help facilitate their ethical implementation. (shrink)

Socio-cultural and political transformations that are taking place in the modern world under the influence of globalization, predetermine the growth of scientific interest in the history and the theory of shaping the group unity.The coverage of various aspects of this problem is found in the works of foreign philosophers (M. Gibernau, S. Huntington, E. Hiddens, B. Yak, et al.), which focus their primary attention on studying the factors, contributing to the emergence of communities in the modern world, while distancing from (...) the development of universal explanatory schemes for the process of forming the collective unity at various stages of the historical development of society.Some Ukrainian researchers (Y. Hrytsak, V. Kravchenko, H. Kasyanov, et al.), who, in contrast to foreign scholars, pay more attention to studying the various aspects of Ukrainian nation-building, are approaching the above problems from a bit different angle of view to solve them. Undoubtedly, the work of these researchers thoroughly and fully covers the history of the formation of the Ukrainian nation, explains the reasons or factors that contributed to its appearance. Meanwhile, they do not have sufficient potential to explain the causes of the cultural fragmentation of modern Ukrainian society, which, in our opinion, has become a logical consequence of the undivided domination in the Ukrainian intellectual discourse of the paradigm of perennialism, within which the cultural identity of the community appears to be a kind of “entity or reality.” Proponents of this position believe that the cultural diversity of nations emerged in the early stages of social development. Within this outlook, Ukrainians, as a mentally and culturally distinct community, have always existed. Of course, their culture has been developing and enriching in the process of historical development and intercultural communication, while its original spiritual and symbolic core remaining unchanged.Despite the fact, that renaissance has a rational grain and can become themethodological basis for very effective national consolidation strategies, one should not ignore its failure to explain the causes of the cultural and civilizational fragmentation of modern Ukrainian society. In our opinion, the solution of this issue requires a comprehensive understanding of the origins, mechanisms and factors, and the formation of a culturally homogeneous Ukrainian cultural space. In view of this, the purpose of our work is to uncover the theoretical preconditions and mechanisms for shaping the cultural identity of Ukrainians in the XIX and early XX centuries. Instead, the task of the work is to highlight the ideological foundations of the growth of scientific interest in folk culture in foreign and Ukrainian intellectual discourse and to reveal their significance in the process of thematizing the modern Ukrainian identity.Methods.The interdisciplinary approach and the principle of unity of the historical and logical have become a methodological basis of scientific research. Methods of historical and philosophical reconstruction, cultural analysis, and extrapolation have been also widely used in the process of research, as well as the fundamental principles of hermeneutics, which have been taken into account.Results. The dominance of the educational enlightenment-cognitive paradigm has contributed to the growth of scientific interest in the cultural identity of peoples, which, according to the prevailing beliefs, has been most clearly preserved in folk poetry and ancient literature. The study of the latter has resulted in the outbreak of ethnographic and linguistic exploration, which facilitated the gradual introduction of the Ukrainian language to literary use, thereby contributing to the thematization of modern Ukrainian identity. (shrink)

Academician Gerasimov devoted his presentation to the problem of improvement and protection of the environment. In his opinion, today, when there is a worldwide threat of exhaustion of natural resources, irreversible pollution, poisoning of the environment, and the impossibility of feeding a growing population, questions of environmental protection and rational use of natural resources are becoming not only an important problem for natural science but a serious social and political matter around which an acute ideological struggle is being waged. Certainly (...) it is a real fact that contemporary mankind is encountering a progressive impairment of the world's ecological situation, caused by the ever more intensive utilization of natural resources under the conditions of rapid scientific and technological progress. Therefore, issues of further rational use of natural resources and improvement and protection of the environment are now becoming problems affecting the everyday interests of the entire population of the earth. (shrink)

The twenty-seven fragments under this number ‘were assembled in the belief that they represented lyric verses in the Aeolic dialect and might contribute something to the text of Sappho or Alcaeus’ . The only feature that is ‘unequivocally Aeolic’ is in fr. 2. 9 the letter following is, or possibly the division is not considered, no doubt rightly). Is this indeed a text in the Aeolic dialect ? There is very little other indication: fr. 4. 3 in fr. 4. 5 (...) would seem decisive if the reading were quite certain. (shrink)

В монографии представлены результаты фундаментального междисциплинарного исследования проблемы смысла жизни, выполненного на стыке общей и управленческой акмеологии, социальной, возрастной, педагогической психологии, психологии управления и труда.

Standard Assessment Tasks are used in the assessment of pupil performance relative to the National Curriculum in England and Wales, assigning pupils to one of 10 levels on various Attainment Targets . This is a criterion‐referenced system, and the conventional reliability measures used in norm‐referenced systems do not apply. This paper discusses the problems involved in aggregating SA T items to give levels, and in measuring the reliability of the outcomes produced. Fitting a simple model to SAT data has allowed (...) reliability measures to be produced which are more relevant to this situation than the single numerical values applied to norm‐referenced tests. (shrink)

Монография посвящена анализу дискурсов и всех сторон взаимодействия реальности с человеком и особенностями его жизнедеятельности. Адресуется специалистам-языковедам, студентам старших курсов и магистрантам.